The Colts played last week without their starting quarterback and running back Anthony Richardson and Jonathan Taylor, and the team was in danger of facing the Titans this week without their top wide receiver, as well. Instead, according to ESPN’s Stephen Holder, Indianapolis is on track to have two of those three players available in Week 6. 
The player who is definitely out this week is Taylor. The rusher showed star potential in his first two years on the team but has been limited due to injury ever since, missing at least six games in each of the past two seasons. Taylor was off to a strong start in 2024, averaging a touchdown per game while also averaging the most yards per game (87.3) since his incredible 2021 campaign.
In Taylor’s absence last week, the Colts ran with two running backs, Trey Sermon and Tyler Goodson, to cover the lost load. They only carried the ball 15 times between the two of them, totaling 64 yards and a touchdown, but both players benefitted from backup quarterback Joe Flacco‘s affinity for check downs, combining to catch all nine of their targets for an additional 56 yards. Should Richardson return this week, the focus may shift back to the run game, requiring much more of Sermon and Goodson.
Speaking of Richardson, Holder reports that the second-year passer is “preparing to return to the lineup.” The 22-year-old participated in the Colts’ last three practices this week, taking a majority of the first-team reps after watching Flacco take all of the first-team reps last week. Flacco had taken over for the injured starter partway through the Steelers matchup in Week 4, leading Indianapolis to a win over his former division-rival. In his spot start last week, Flacco went blow-for-blow against Trevor Lawrence and the Jaguars in a shootout that saw him complete 75 percent of his passes for 359 yards and three touchdowns.
It may be a bit surprising to see Indianapolis go back to Richardson, who sports a 50.6 completion percentage on the season and has thrown only three touchdowns while leading the league with six interceptions. Based on the draft capital invested in Richardson and the fact that he was the quarterback working with the first-team offense all summer, it makes sense for the team to stick with him a bit longer as he gets healthy. If he continues to struggle running an NFL offense, though, the wily veteran, Flacco, sits patiently capable on the bench.
Lastly, Holder provided an update on top wideout Michael Pittman Jr. As he’s dealt with “a nagging back injury” to start the season, per Jordan Schultz of Bleacher Report, Pittman was in danger of missing extended time for the time since his rookie year. All signs were pointing towards a stint on injured reserve for the veteran receiver, but it appears that he will instead tough it out and try to play through the injury.
The Colts’ receiving game has been dominated so far this season by Pittman, Josh Downs, and Alec Pierce. In theory the team has some untested depth at the position with rookie second-round pick Adonai Mitchell and veteran Ashton Dulin, but with Pittman playing through his injury, Indianapolis can continue to rely on their top three.